The San Francisco 49ers will usher in the Trey Lance era Week 1 against the Chicago Bears, and, with Deebo Samuel still in the picture, everything appears to be coming together for the team.

The 49ers boast a fearsome defense with Nick Bosa, Javon Kinlaw and Fred Warner among those holding down the fort.

The team came just short of a Super Bowl bid last year and will likely be back in that same mix this season. Week 4 and Week 8 both feature an NFC championship rematch between the Niners and Los Angeles Rams. 

Read below for the 49ers’ schedule, how to watch games and where to watch.

Deebo Samuel (19) of the San Francisco 49ers runs after a catch for a touchdown against the Los Angeles Rams in the NFC championship game at SoFi Stadium Jan. 30, 2022, in Inglewood, Calif.
(Christian Petersen/Getty Images)

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Week 1: San Francisco 49ers @ Chicago Bears, September 11, 2022

TV: FOX

Time: 1 p.m. ET

Week 2: San Francisco 49ers vs. Seattle Seahawks, September 18, 2022

TV: FOX

Time: 4:05 p.m. ET

Week 3: San Francisco 49ers @ Denver Broncos, September 25, 2022

TV: NBC

Time: 8:20 p.m. ET

Week 4: San Francisco 49ers vs. Los Angeles Rams, October 3, 2022

TV: ESPN

Time: 8:15 p.m. ET

Week 5: San Francisco 49ers @ Carolina Panthers, October 9, 2022

TV: CBS

Time: 4:05 p.m. ET

Week 6: San Francisco 49ers @ Atlanta Falcons, October 16, 2022

TV: FOX

Time: 1 p.m. ET

Week 7: San Francisco 49ers vs. Kansas City Chiefs, October 23, 2022

TV: FOX

Time: 4:25 p.m. ET

Week 8: San Francisco 49ers @ Los Angeles Rams, October 30, 2022

TV: FOX

Time: 4:25 p.m. ET

Week 9: BYE

Week 10: San Francisco 49ers vs. Los Angeles Chargers, November 13, 2022

TV: NBC

Time: 8:20 p.m. ET

Week 11: San Francisco 49ers vs. Arizona Cardinals, November 21, 2022

TV: ESPN

Time: 8:15 p.m. ET

Week 12: San Francisco 49ers vs. New Orleans Saints, November 27, 2022

TV: FOX

Time: 4:25 p.m. ET

Week 13: San Francisco 49ers vs. Miami Dolphins, December 4, 2022

TV: FOX

Time: 4:05 p.m. ET

Week 14: San Francisco 49ers vs. Tampa Bay Buccaneers, December 11, 2022

TV: FOX

Time: 4:25 p.m. ET

Week 15: San Francisco 49ers @ Seattle Seahawks, December 15, 2022

TV: Amazon Prime

Time: 8:15 p.m. ET

Week 16: San Francisco 49ers vs. Washington Commanders, December 24, 2022

TV: CBS

Time: 4:05 p.m. ET

Week 17: San Francisco 49ers @ Las Vegas Raiders, January 1, 2023

TV: FOX

Time: 4:05 p.m. ET

Week 18: San Francisco 49ers vs. Arizona Cardinals, January 8, 2023

TV: TBD

Time: TBD

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